It's possible to have Slime Rancher freeze/stop responding while loading larger save files. Most of the time, this is actually an issue with the load screen specifically, and the game is still processing the load of your save file in the background.
As a note, if you have other applications or games open on your system, completely closing them may reduce the time you need to wait.
If after a few minutes it's still not loading, we suggest you submit a ticket to us describing the situation, along with any system information you can provide. If you can provide the amount of time you've waited for the issue to resolve, that can be helpful in diagnosing the issue.